Publications

2025

Kurg, Kristiina. PhD thesis. Exploring the potential of a liquid biopsy approach for melanoma diagnostics and the role of extracellular vesicles in atherosclerosis development. University of Tartu Press. Defended 28.01.2025
Kurg, Kristiina (2025). Haigustekitajate määramine hingamisteede haiguste diagnostikas. Perearst, 03 (210), 44−47.
Kurg, Kristiina (2025). Alkoholi tarvitamine ja laborianalüüsid. Lege Artis, 3 (9), 29−32.

2024

Ernits, M., Reinsalu, O., Yandrapalli, N. et al. Microfluidic production, stability and loading of synthetic giant unilamellar vesicles. Sci Rep 14, 14071 (2024). https://doi.org/10.1038/s41598-024-64613-4
Brūmele, B.; Serova, E.; Lupp, A.; Suija, M.; Mutso, M.; Kurg, R. Cross-Reactivity of N6AMT1 Antibodies with Aurora Kinase A: An Example of Antibody-Specific Non-Specificity. Antibodies 2024, 13, 33. https://doi.org/10.3390/antib13020033
Ianevski A, Frøysa IT, Lysvand H, Calitz C, Smura T, Schjelderup Nilsen HJ, Høyer E, Afset JE, Sridhar A, Wolthers KC, Zusinaite E, Tenson T, Kurg R, Oksenych V, Galabov AS, Stoyanova A, Bjørås M, Kainov DE. The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants. Antiviral Res. 2024 Feb 26:105842. doi: 10.1016/j.antiviral.2024.105842.
Mutso M, Brūmele B, Serova E, Väärtnõu F, Suija M, Kurg R. The methyltransferase N6AMT1 participates in the cell cycle by regulating cyclin E levels. PLoS One. 2024 Feb 23;19(2):e0298884. doi: 10.1371/journal.pone.0298884.
Kurg, Kristiina (2024). The Arctic Experience 2024. Klinisk Biokemi i Norden, 36 (2), 24−27.
Kurg, Kristiina (2024). Kroonilise südamehaigusega patsiendi laboratoorsete analüüside määramine. Perearst, 02 (198), 38−41
Kurg, Kristiina (2024). Nahavähi diagnoosimiseks võib piisata tulevikus veretilgast. ERR Novaator, 26.01.2024.
Kurg, Kristiina (2024). Preanalüütilised vead analüüside võtmisel ja nende esinemissagedus. Pereõde, 3 (47), 28−30.
Samel, Anneli. PhD thesis. Unveiling the characteristics of cancer-testis antigen MAGEA10. University of Tartu Press. Defended 9.02.2024

2023

Samel A, Väärtnõu F, Verk L, Kurg K, Mutso M, Kurg R. How the Intrinsically Disordered N-Terminus of Cancer/Testis Antigen MAGEA10 Is Responsible for Its Expression, Nuclear Localisation and Aberrant Migration. Biomolecules. 2023; 13(12):1704. https://doi.org/10.3390/biom13121704
Ravlo E, Ianevski A, Starheim E, Wang W, Ji P, Lysvand H, Smura T, Kivi G, Voolaid ML, Plaan K, Ustav M, Ustav M Jr, Zusinaite E, Tenson T, Kurg R, Oksenych V, Walstad K, Nordbø SA, Kaarbø M, Ernits K, Bjørås M, Kainov DE, Høysæter Fenstad M. Boosted production of antibodies which neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following mRNA vaccination – a case study. Int J Infect Dis. 2023 Oct 16:S1201-9712(23)00748-8. doi: 10.1016/j.ijid.2023.10.011.
Kurg, Kristiina (2023). Sagedamini kasutatavad ravimid, mis vajavad kõrvaltoimete tõttu laboratoorset jälgimist. Lege Artis, 3 (7), 41−46.
Kurg, Kristiina (2023). Hemogrammi tõlgendamine. Perearst, 03 (188), 58−62.

2022

Kurg, Kristiina, Anu Planken, and Reet Kurg. 2022. “Proteomic and Biochemical Analysis of Extracellular Vesicles Isolated from Blood Serum of Patients with Melanoma” Separations 9, no. 4: 86. https://doi.org/10.3390/separations9040086
Žėkas, Vytautas; Kurg, Reet; Kurg, Kristiina; Bironaitė, Daiva; Radzevičius, Mantas; Karčiauskaitė, Dovilė; Matuzevičienė, Rėda; Kučinskienė, Zita Aušrelė (2022). Oxidative Properties of Blood-Derived Extracellular Vesicles in 15 Patients After Myocardial Infarction. Medical Science Monitor, 28, e935291. DOI: 10.12659/MSM.935291.
Kurg, Kristiina (2022). Kiiranalüüsid pereõe töös. Pereõde, 37 (1), 40−42.
Kurg, Kristiina (2022). Sagedamini kasutatavad ravimid, mis vajavad kõrvaltoimete tõttu laboratoorset jälgimist. Perearst, 8, 69−74.
“Tartu Ülikooli Tehnoloogiainstituut – kaks aastakümmet teaduse eesliinil” Tartu Ülikooli Kirjastus.
Reinsalu, Olavi. PhD thesis, Cancer-testis antigen MAGE-A4 is incorporated into extracellular vesicles and is exposed to the surface, University of Tartu Press, defended 16.08.2022

2021

Brūmele, Baiba; Mutso, Margit; Telanne, Lilian; Õunap, Kadri; Spunde, Karīna; Abroi, Aare; Kurg, Reet (2021). Human TRMT112-Methyltransferase Network Consists of Seven Partners Interacting with a Common Co-Factor. Int. J. Mol. Sci. 2021, 22, 13593. https://doi.org/10.3390/ijms222413593
Erenpreisa, Jekaterina; Krigerts, Jekabs; Salmina, Kristine; Gerashchenko, Bogdan I.; Freivalds, Talivaldis; Kurg, Reet; Winter, Ruth; Krufczik, Matthias; Zayakin, Pawel; Hausmann, Michael; Giuliani, Alessandro (2021). Heterochromatin Networks: Topology, Dynamics, and Function (a Working Hypothesis). Cells 10, (7): 1582. https://doi.org/10.3390/cells10071582
Reinsalu, Olavi; Samel, Anneli; Niemeister, Elen; Kurg, Reet (2021). MAGEA4 Coated Extracellular Vesicles Are Stable and Can Be Assembled In Vitro. Int. J. Mol. Sci. 2021, 22(10), 5208; https://doi.org/10.3390/ijms22105208
Kurg, Kristiina (2021) Analüüside kordamine dünaamikas. Perearst, 165 (2), 58−61.
Kurg, Kristiina (2021). Laborianalüüside tulemuste tõlgendamine. Pereõde, 3, 27−30.
Kurg, Kristiina (2021). Sagedasemaste vereanalüüside vastuste tõlgendamine. Pereõde, 59−61.

2020

Ianevski A, Yao R, Biza S, Zusinaite E, Mannik A, Kivi G, Planken A, Kurg K, Tombak EM, Ustav M Jr, Shtaida N, Kulesskiy E, Jo E, Yang J, Lysvand H, Løseth K, Oksenych V, Aas PA, Tenson T, Vitkauskienė A, Windisch MP, Fenstad MH, Nordbø SA, Ustav M, Bjørås M, Kainov DE. Identification and Tracking of Antiviral Drug Combinations. Viruses. 2020 Oct 18;12(10):1178. doi: 10.3390/v12101178.
Kurg, Kristiina; Kurg, Reet (2020). Melanoomi diagnoos vaid veretilgast? Kodutohter, 24−28.
Kurg, Kristiina; Kurg, Reet (2020). Skin cancer diagnostics from just a drop of blood – could it really be true? Research in Estonia, 05.11.2020.

2019

Kuldkepp, Anneli; Karakai, Magda; Toomsoo, Eve; Reinsalu, Olavi; Kurg, Reet (2019). Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells. Oncotarget, 10 (38), 3694−3708.10.18632/oncotarget.26979.
Leetsi, L ; Õunap, K; Abroi, A; Kurg, R (2019). The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells. Biomolecules, 9 (9), 422. DOI: 10.3390/biom9090422.
Salmina, Kristine; Kurg, Reet; Krigerts, Jekabs; Erenpreisa, Jekaterina (2019). The topological relationship between ribogenesis, mRNA transcription/splicing and the tension of actin cytoskeletion. Biopolymers and Cell 35(3):231-232. 10.7124/bc.0009F7.

2018

Õunap, Kadri; Kurg, Kristiina; Võsa, Liisi; Maiväli, Ülo; Teras, Marina; Planken, Anu; Ustav, Mart; Kurg, Reet (2018). Antibody response against cancer‑testis antigens MAGEA4 and MAGEA10 in patients with melanoma. Oncology Letters, 16 (1), 211−2018. DOI: 10.3892/ol.2018.8684.

2017

Õunap, Kadri. PhD thesis. The Williams-Beuren syndrome chromosome region protein WBSCR22 is a ribosome biogenesis factor. University of Tartu press. Defended 22.05.2017

2016

Kurg, Reet; Reinsalu, Olavi; Jagur, Sergei; Õunap, Kadri; Võsa, Liisi; Kasvandik, Sergo; Padari, Kärt; Gildemann, Kiira; Ustav, Mart (2016). Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Scientific Reports, 6 (29245), 1−11. DOI: 10.1038/srep29425.
Kivipõld, Piia. PhD thesis. Studies on the Role of Papillomavirus E2 Proteins in Virus DNA Replication. University of Tartu Press. Defended 12.12.2016

2015

Õunap, K.; Leetsi, L.; Matsoo, M.; Kurg, R. (2015). The Stability of Ribosome Biogenesis Factor WBSCR22 Is Regulated by Interaction with TRMT112 via Ubiquitin-Proteasome Pathway. PLoS ONE, 10 (7), e0133841. DOI: 10.1371/journal.pone.0133841.
Kivipõld, P.; Võsa, L.; Ustav, M.; Kurg, R. (2015). DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells. Virology Journal, 12, 104.10.1186/s12985-015-0335-z.
Sankovski, Eve; Karro, Kristiina; Sepp, Mari; Kurg, Reet; Ustav, Mart; Abroi, Aare (2015). Characterization of the nuclear matrix targeting sequence (NMTS) of the BPV1 E8/E2 protein – the shortest known NMTS. Nucleus, 289−300. DOI: 10.1080/19491034.2015.1074359.

2013

Õunap, Kadri; Käsper, Ly; Kurg, Ants; Kurg, Reet (2013). The human WBSCR22 protein is involved in the biogenesis of the 40S ribosomal subunits in mammalian cells. PLoS ONE, 8 (9), nr e75686. DOI: 10.1371/journal.pone.0075686.

2012

Võsa, L; Sudakov, A; Remm, M; Ustav, M; Kurg, R. (2012). Identification and analysis of papillomavirus E2 protein binding sites in the human genome. Journal of Virology, 86 (1), 348−357. DOI: 10.1128/JVI.05606-11.
Järving, R.; Lõokene, A.; Kurg, R.; Siimon, L.; Järving, I.; Samel, N. (2012). Activation of 11R-lipoxygenase is fully Ca(2+)-dependent and controlled by the phospholipid composition of the target membrane. Biochemistry, 51 (15), 3310−3320. DOI: 10.1021/bi201690z.

2011

Kurg, R. (2011). The role of E2 proteins in papillomavirus DNA replication. In: Seligmann, H. (Ed.). DNA Replication – Current Advances (613−638).. Rijeka, Croatia: INTECH.
Kurg, Reet (2011). INEPO-l kohtuvad keskkonnahuvilised noored. Eesti Loodus, 8.

2010

Kurg, R; Uusen, P; Võsa, L; Ustav, M (2010). Human papillomavirus E2 protein with single activation domain initiates HPV18 genome replication, but is not sufficient for long-term maintenance of virus genome. Virology, 408 (2), 159−166.10.1016/j.virol.2010.09.010.

2009

Varvas, K.; Kurg, R.; Hansen, K.; Järving, R.; Järving, I.; Valmsen, K.; Lõhelaid, H.; Samel, N. (2009). Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: Genetic and biochemical characterization of two crustacean cyclooxygenases. Insect Biochemistry and Molecular Biology, 39 (12), 851−860.
Kurg, R.; Uusen, P.; Sepp, T.; Sepp, M.; Abroi, A.; Ustav, M. (2009). Bovine papillomavirus type 1 E2 protein heterodimer is functional in papillomavirus DNA replication in vivo. Virology, 386 (2), 353−359. DOI: 10.1016/j.virol.2009.01.025.

2008

Hansen, K.; Kurg, R.; Varvas, K.; Valmsen, K.; Järving, I.; Järving, R.; Samel, N. (2008). Cloning, expression and characterization of cyclooxygenase gene from amphipods. FEBS Journal: Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference. Athens, GREECE, JUN 28-JUL 03, 2008. , 403. (275).

2007

Denks, K.; Späeth, E.L.; Jõers, K.; Randoja, R.; Talpsep, T.; Ustav, M.; Kurg, R. (2007). Coinfection of Chlamydia trachomatis, Ureaplasma urealyticum and human papillomavirus among patients attending STD clinics in Estonia. Scandinavian Journal of Infectious Diseases, 39 (8), 714−718.
Hansen, K.; Kurg, R.; Varvas, K.; Järving, I.; Järving, R.; Valmsen, K.; Samel, N. (2007). Tsüklooksügenaas kirpvähilistest: kloneerimine, ekspresseerimine ja iseloomustamine. XXX Eesti Keemiapäevad Teaduskonverentsi teesid: XXX Eesti Keemiapäevad Tartus 16. november 2007. Toim. Rinken, A. Tartu: Tartu Ülikooli Kirjastus, 30−31.

2006

Kurg, R; Tekkel, Helena; Abroi, Aare; Ustav, Mart (2006). Characterizarion of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers. Journal of Virology, 80 (22), 11218−11225.

2005

Kurg, R.; Sild, K.; Ilves, A.; Sepp, M.; Ustav, M. (2005). Association of bovine papillomavirus E2 protein with nuclear structures in vivo. Journal of Virology, 79 (16), 10528−10539.

2004

Jarving, R.; Jarving, I.; Kurg, R.; Brash, AR.; Samel, N. (2004). On the evolutionary origin of cyclooxygenase (COX) isozymes – Characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. Journal of Biological Chemistry, 279 (14), 13624−13633.

2001

Kivimae, S.; Allikas, A.; Kurg, R.; Ustav, M. (2001). Replication of a chimeric origin containing elements from Epstein-Barr virus ori P and bovine papillomavirus minimal origin. Virus Research, 75 (1), 1−11.
Allikas, A.; Ord, D.; Kurg, R.; Kivi, S.; Ustav, M. (2001). Roles of the hinge region and the DNA binding domain of the bovine papillomavirus type 1 E2 protein in initiation of DNA replication. Virus Research, 75 (2), 95−106.
Koljak, R.; Jarving, I.; Kurg, R.; Boeglin, WE.; Varvas, K.; Valmsen, K.; Ustav, M.; Brash, AR.; Samel, N. (2001). The basis of prostaglandin synthesis in coral – Molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa. Journal of Biological Chemistry, 276 (10), 7033−7040.

2000

Kurg, R.; Langel, U.; Ustav, M. (2000). Inhibition of the bovine papillomavirus E2 protein activity by peptide nucleic acid. Virus Research, 66 (1), 39−50.
Kurg, R; Ustav, M. (2000). Update to: Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Epitope Tags. Lu,Q.; M.P. Weiner. Cloning and Expression Vectors for Protein Studies (Chapter 27). . Weiner: Eaton Publishing Co.

1999

Abou-Zahr, F.; Bejjani, B.; Kruyt, FAE.; Kurg, R.; Bacino, C.; Shapira, SK.; Youssoufian, H. (1999). Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. American Journal of Medical Genetics, 83 (5), 388−391.
Kurg, R.; Parik, J.; Juronen, E.; Sedman, T.; Abroi, A.; Liiv, I.; Langel, U.; Ustav, M. (1999). Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication. Journal of Virology, 73 (6), 4670−4677.

1996

Abroi, A.; Kurg, R.; Ustav, M. (1996). Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. Journal of Virology, 70 (9), 6169−6179.